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Review article

Osteoporosis therapy using nanoparticles: a review

Abstract

Osteoporosis, characterized by low bone density and increased risk of fractures, represents a major healthcare challenge. Anti-resorptive and anabolic medications are now used to treat osteoporosis in an effort to reduce bone loss and increase bone mass. Innovative methods are required since current therapies have drawbacks. Promising options for improving bone health and medicine delivery are provided by nanotechnology. Bisphosphonates with tetracyclines and oligopeptides, among other compounds that target the bone, make it easier to provide a particular medication to bone tissue. Additionally, nanocarriers are essential for the administration of both organic and inorganic nanoparticles in the treatment of osteoporosis. Drug encapsulation and controlled release may be done in a variety of ways using organic nanoparticles. Inorganic nanoparticles have special qualities that help in medication transport and bone repair. This review explores the potential of nanoparticle-based strategies in the treatment of osteoporosis.

Details

Original languageEnglish
JournalAnnals of Medicine and Surgery
Volume86
Issue number1
Pages284-291
PublisherWolters Kluwer
ISSN2049-0801
DOI10.1097/ms9.0000000000001467
Publication statusPublished — 1 November 2023

Keywords

UN Sustainable Development Goals

  • 3 — Good health and well-being

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